Blar i forfatter "Ågmo, Anders"
-
Estrogen receptors α and β in the central amygdala and the ventromedial nucleus of the hypothalamus: Sociosexual behaviors, fear and arousal in female rats during emotionally challenging events
Le Moëne, Olivia; Stavarache, Mihaela; Ogawa, Sonoko; Musatov, Sergei; Ågmo, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-27)Estrogens receptors (ER) are involved in several sociosexual behaviors and fear responses. In particular, the ERα is important for sexual behaviors, whereas ERβ modulates anxiolytic responses. Using shRNA directed either against the ERα or the ERβ RNAs (or containing luciferase control) encoded within an adeno-associated viral vector, we silenced these receptors in the ventromedial nucleus of the ... -
Rapid changes in sociosexual behaviors around transition to and from behavioral estrus, in female rats housed in a seminatural environment
Le Moene, Olivia; Hernandez-Arteaga, Enrique; Chu, Xi; Ågmo, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-28)Gonadally intact female rats display sexual behaviors only during a portion of the estrus cycle. In standard experimental setups, the on- and offset of sexual behavior is gradual. However, in naturalistic settings, it is almost instantaneous. We assessed the changes in sociosexual behaviors at the beginning and end of behavioral estrus in ovariectomized females treated with ovarian hormones. Rats ... -
Sexual Incentive Motivation and Copulatory Behavior in Male Rats Treated With the Adrenergic α2-Adrenoceptor Agonists Tasipimidine and Fadolmidine: Implications for Treatment of Premature Ejaculation
Lehtimäki, Jyrki; Ventura-aquino, Elisa; Chu, Xi; Paredes, Raul G.; Ågmo, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-04)<p><i>Background:</i> Premature ejaculation is the most common sexual dysfunction in young men, and it often leads to reduced relationship satisfaction and quality of life. <p><i>Aim:</i> To determine the role of central and peripheral α2-adrenoceptors in the control of ejaculation and sexual incentive motivation in rats. <p><i>Methods:</i> Sexual incentive motivation was studied in a large arena ...